Terazosin Analogs Targeting Pgk1 as Neuroprotective Agents: Design, Synthesis, and Evaluation
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DOI: 10.3389/fchem.2022.906974
Abstract: Nitrogen-containing heterocyclic compounds have shown promising therapeutic effects in a variety of inflammatory and neurodegenerative diseases. Recently, terazosin (TZ), a heterocyclic compound with a quinazoline core, was found to combine with phosphoglycerol kinase 1 (Pgk1)… read more here.
Keywords: targeting pgk1; terazosin analogs; neuroprotective agents; analogs targeting ... See more keywords