A Comprehensive Study of the Interaction between Peptidoglycan Fragments and the Extracellular Domain of Mycobacterium tuberculosis Ser/Thr Kinase PknB
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DOI: 10.1002/cbic.201700385
Abstract: The Mycobacterium tuberculosis Ser/Thr kinase PknB is implicated in the regulation of bacterial cell growth and cell division. The intracellular kinase function of PknB is thought to be triggered by peptidoglycan (PGN) fragments that are… read more here.
Keywords: kinase; spectroscopy; pknb; pgn ... See more keywords
Synthesis, thermal stability and kinetic decomposition of triblock copolymer polypropylene glycol–poly glycidyl nitrate–polypropylene glycol (PPG–PGN–PPG)
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DOI: 10.1007/s00289-019-03051-z
Abstract: An energetic triblock copolymer PPG–PGN–PPG (Mn = 1886 g mol−1) was synthesized for the first time by cationic ring-opening polymerization of propylene oxide with low molecular weight poly glycidyl nitrate (PGN) (Mn = 1061 g mol−1) as a macroinitiator,… read more here.
Keywords: triblock copolymer; polypropylene glycol; pgn; ppg ... See more keywords
Expression of osteoclastogenic and anti-osteoclastogenic cytokines differs in mouse gingiva injected with lipopolysaccharide, peptidoglycan, or both.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2020.104990
Abstract: OBJECTIVE Bacterial substances in subgingival biofilm evoke alveolar bone resorption. We previously reported that gingival injection of bacterial lipopolysaccharide (LPS) and peptidoglycan (PGN) induced alveolar bone resorption in mice. However, the mechanism by which LPS… read more here.
Keywords: lps pgn; expression; pgn; bone resorption ... See more keywords
Dietary muramidase degrades bacterial peptidoglycan to NOD-activating muramyl dipeptides and reduces duodenal inflammation in broiler chickens
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Nutrition"
DOI: 10.1017/s0007114520004493
Abstract: Abstract Muramidases constitute a superfamily of enzymes that hydrolyse peptidoglycan (PGN) from bacterial cell walls. Recently, a fungal muramidase derived from Acremonium alcalophilum has been shown to increase broiler performance when added as a feed… read more here.
Keywords: broiler; muramidase degrades; muramidase; shown muramidase ... See more keywords
The bacterial peptidoglycan-sensing molecule Pglyrp2 modulates brain development and behavior
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DOI: 10.1038/mp.2016.182
Abstract: Recent studies have revealed that the gut microbiota modulates brain development and behavior, but the underlying mechanisms are still poorly understood. Here, we show that bacterial peptidoglycan (PGN) derived from the commensal gut microbiota can… read more here.
Keywords: development behavior; pgn; pglyrp2; brain development ... See more keywords
PGN_0298 in the Assembly and Insertion Machinery (Aim) Operon Is Essential for the Viability of Porphyromonas gingivalis.
Sign Up to like & getrecommendations! Published in 2025 at "Microbiology and immunology"
DOI: 10.1111/1348-0421.70021
Abstract: Porphyromonas gingivalis is a typical periodontal pathogen, and one of its key virulence factors is the powerful protease gingipains. Gingipains are secreted via the type IX secretion system (T9SS) and are associated with the assembly… read more here.
Keywords: assembly insertion; pgn; pgn 0298; insertion machinery ... See more keywords
Abstract 3527: Paraneoplastic glomerulonephropathies associated with solid tumor: A review of published literature
Sign Up to like & getrecommendations! Published in 2020 at "Epidemiology"
DOI: 10.1158/1538-7445.am2020-3527
Abstract: Background: Paraneoplastic glomerulonephropathies (PGN) are paraneoplastic syndromes associated with solid tumors and hematologic malignancies. PGN is difficult to differentiate from other forms of glomerulonephropathies and standard management of glomerulonephropathies is often ineffective. A delay in… read more here.
Keywords: solid tumor; paraneoplastic glomerulonephropathies; cancer; associated solid ... See more keywords
AhR Regulates Peptidoglycan-Induced Inflammatory Gene Expression in Human Keratinocytes.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of innate immunity"
DOI: 10.1159/000517627
Abstract: Bacterial peptidoglycan (PGN) stimulates toll-like receptor 2 (TLR2) on the surface of keratinocytes (KCs), triggering signaling pathways that promote an innate immune response. However, excessive TLR2 activation can lead to inappropriate inflammation, which contributes to… read more here.
Keywords: response; inflammatory gene; ahr; gene expression ... See more keywords
Monocyte procoagulant responses to anthrax peptidoglycan are reinforced by proinflammatory cytokine signaling.
Sign Up to like & getrecommendations! Published in 2019 at "Blood advances"
DOI: 10.1182/bloodadvances.2019000513
Abstract: Disseminated intravascular coagulation is a frequent manifestation during bacterial infections and is associated with negative clinical outcomes. Imbalanced expression and activity of intravascular tissue factor (TF) is central to the development of infection-associated coagulopathies. Recently,… read more here.
Keywords: procoagulant responses; anthrax peptidoglycan; recognition; expression ... See more keywords
Novel fimbrilin PGN_1808 in Porphyromonas gingivalis
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DOI: 10.1371/journal.pone.0173541
Abstract: Porphyromonas gingivalis, a periodontopathic gram-negative anaerobic bacterium, generally expresses two types of fimbriae, FimA and Mfa1. However, a novel potential fimbrilin, PGN_1808, in P. gingivalis strain ATCC 33277 was recently identified by an in silico… read more here.
Keywords: fimbrilin pgn; porphyromonas gingivalis; fima mfa1; pgn 1808 ... See more keywords
Synthesis and Thermal Decomposition Kinetics of Epoxy Poly Glycidyl Nitrate as an Energetic Binder
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DOI: 10.14429/dsj.70.15470
Abstract: An energetic binder epoxy poly glycidyl nitrate (e-PGN) with a molecular weight of about 1244 gr/mol was synthesised via end modified poly glycidyl nitrate (PGN) is presented in the paper. This structure was characterised by… read more here.
Keywords: glycidyl nitrate; poly glycidyl; binder; pgn ... See more keywords