Effects of cholesterol content on activity of P-glycoproteins and membrane physical state, and consequences for anthelmintic resistance in the nematode Haemonchus contortus
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DOI: 10.1051/parasite/2019079
Abstract: Eukaryote plasma membranes protect cells from chemical attack. Xenobiotics, taken up through passive diffusion, accumulate in the membranes, where they are captured by transporters, among which P-glycoproteins (Pgps). In nematodes such as Haemonchus contortus, eggshells… read more here.
Keywords: cholesterol content; pgp activity; resistance; haemonchus contortus ... See more keywords