The Structural Integrity of Plasmid-Encoded Pgp3 Is Essential for Induction of Hydrosalpinx by Chlamydia muridarum
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2019.00013
Abstract: Pgp3 consists of globular N- and C-terminal domains connected by a triple-helical coiled-coil middle domain. We demonstrated previously that Pgp3 is required for induction of hydrosalpinx by Chlamydia muridarum. We constructed C. muridarum transformants harboring… read more here.
Keywords: muridarum; induction hydrosalpinx; pgp3; hydrosalpinx ... See more keywords
Efficacy of Pgp3 vaccination for Chlamydia urogenital tract infection depends on its native conformation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1018774
Abstract: Urogenital tract infections with Chlamydia trachomatis have frequently been detected among patients diagnosed with sexually transmitted infections, and such infections lead to inflammatory complications. Currently, no licensed chlamydial vaccine is available in clinical practice. We… read more here.
Keywords: urogenital tract; tract infection; tract; pgp3 ... See more keywords