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A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure

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Published in 2017 at "Immunity"

DOI: 10.1016/j.immuni.2017.03.017

Abstract: &NA; Broadly neutralizing antibodies (bnAbs) to HIV delineate vaccine targets and are prophylactic and therapeutic agents. Some of the most potent bnAbs target a quaternary epitope at the apex of the surface HIV envelope (Env)… read more here.

Keywords: apex; antibody; structure; broadly neutralizing ... See more keywords