Characterization of PGua4, a Guanidinium-Rich Peptoid that Delivers IgGs to the Cytosol via Macropinocytosis.
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DOI: 10.1021/acs.molpharmaceut.2c00783
Abstract: To investigate the structure-cellular penetration relationship of guanidinium-rich transporters (GRTs), we previously designed PGua4, a five-amino acid peptoid containing a conformationally restricted pattern of eight guanidines, which showed high cell-penetrating abilities and low cell toxicity.… read more here.
Keywords: characterization pgua4; peptoid; macropinocytosis; guanidinium rich ... See more keywords