Clinical Implications of Pharmacogenomic Testing in the Real World-Insights From a Pediatric Program.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2021.10467
Abstract: Pharmacogenomics aims to improve medication safety and dosing by incorporating the guidance of patients’ genetic information into treatment decisions. While pharmacogenomic (PGx) testing has become more widely available and less costly, its use in routine… read more here.
Keywords: information; pgx; treatment; drug ... See more keywords
Confirmatory DPYD Testing in Patients Receiving Fluoropyrimidines who are Suspected DPYD Variant Carriers Based on a Genetic Data Repository.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical pharmacology and therapeutics"
DOI: 10.1002/cpt.2936
Abstract: Using pharmacogenetics (PGx) to inform clinical decision making can benefit patients but clinical use of PGx testing has been limited. Existing genetics data obtained in the course of research could be used to identify patients… read more here.
Keywords: dpyd; dpyd testing; data repository; suspected dpyd ... See more keywords
Integrating pharmacogenetic testing into primary care
Sign Up to like & getrecommendations! Published in 2017 at "Expert Review of Precision Medicine and Drug Development"
DOI: 10.1080/23808993.2017.1398046
Abstract: ABSTRACT Introduction: Pharmacogenetic (PGx) testing has greatly expanded due to enhanced understanding of the role of genes in drug response and advances in DNA-based testing technology development. As many primary care visits result in a… read more here.
Keywords: medicine; primary care; pharmacogenetic testing; integrating pharmacogenetic ... See more keywords
Implementation of Pharmacogenomics- Where are we now?
Sign Up to like & getrecommendations! Published in 2022 at "British journal of clinical pharmacology"
DOI: 10.1111/bcp.15591
Abstract: Pharmacogenomics (PGx), examining the effect of genetic variation on interpatient variation in drug disposition and response, has been widely studied for several decades. However, as cost, as well as turnaround time associated with PGx testing,… read more here.
Keywords: pharmacology; pgx testing; implementation pharmacogenomics; pgx ... See more keywords
The coming‐of‐age of pharmacogenetic testing in clinical psychiatry
Sign Up to like & getrecommendations! Published in 2019 at "Psychiatry and Clinical Neurosciences"
DOI: 10.1111/pcn.12832
Abstract: Pharmacogenetic (PGx) testing is key to addressing the issue of the prevailing ‘trial-and-error’ prescribing of medications in psychiatry. Expert groups have reported high evidence levels for several gene–drug pairs related to psychotropic medications with most… read more here.
Keywords: pgx; treatment; pgx testing; pgx tests ... See more keywords
Application of Pharmacogenomics Testing in a Community-based Facility
Sign Up to like & getrecommendations! Published in 2023 at "Hospital Pharmacy"
DOI: 10.1177/00185787221134693
Abstract: This study was designed to examine the use of pharmacogenomics (PGx) testing in a community-based facility, the adoption of the PGx recommendations by providers, and assess challenges and opportunities for pharmacists in using PGx testing… read more here.
Keywords: testing community; based facility; pgx testing; pgx test ... See more keywords
Lack of exposure to pharmacogenomics education among the health care providing students in the West Bank of Palestine
Sign Up to like & getrecommendations! Published in 2023 at "Drug Metabolism and Personalized Therapy"
DOI: 10.1515/dmpt-2022-0180
Abstract: Abstract Objectives Evaluating the knowledge in pharmacogenomics (PGx) is the first step toward the implementation of PGx testing in clinical practice. This survey aimed to evaluate the knowledge of PGx testing among healthcare providing students… read more here.
Keywords: west bank; bank palestine; pgx testing; medicine ... See more keywords
Pharmacogenomic Testing In Pediatrics: Navigating The Ethical, Social, And Legal Challenges
Sign Up to like & getrecommendations! Published in 2019 at "Pharmacogenomics and Personalized Medicine"
DOI: 10.2147/pgpm.s179172
Abstract: Abstract For the past several years, the implementation of pharmacogenetic (PGx) testing has become widespread in several centers and clinical practice settings. PGx testing may be ordered at the point-of-care when treatment is needed or… read more here.
Keywords: navigating ethical; ethical social; pgx testing; testing pediatrics ... See more keywords
Independent Community Pharmacists’ Experience in Offering Pharmacogenetic Testing
Sign Up to like & getrecommendations! Published in 2021 at "Pharmacogenomics and Personalized Medicine"
DOI: 10.2147/pgpm.s314972
Abstract: Objective This study assessed pharmacist experiences with delivering pharmacogenetic (PGx) testing in independent community pharmacies. Methods We conducted a cluster randomized trial of independent community pharmacies in North Carolina randomized to provide either PGx testing… read more here.
Keywords: experience; study; independent community; pgx testing ... See more keywords
Attitudes toward pharmacogenetics in patients undergoing CYP2C19 testing following percutaneous coronary intervention.
Sign Up to like & getrecommendations! Published in 2022 at "Personalized medicine"
DOI: 10.2217/pme-2021-0064
Abstract: Aim: Patient knowledge and attitudes toward pharmacogenetic (PGx) testing may impact adoption of clinical testing. Methods: Questionnaires regarding knowledge, attitudes and ethics of PGx testing were distributed to 504 patients enrolled in the ADAPT study… read more here.
Keywords: attitudes toward; toward pharmacogenetics; pgx testing; knowledge ... See more keywords
Implementing Pharmacogenetic Testing in Gastrointestinal Cancers (IMPACT-GI): Study Protocol for a Pragmatic Implementation Trial for Establishing DPYD and UGT1A1 Screening to Guide Chemotherapy Dosing
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.859846
Abstract: Background Fluoropyrimidines (fluorouracil [5-FU], capecitabine) and irinotecan are commonly prescribed chemotherapy agents for gastrointestinal (GI) malignancies. Pharmacogenetic (PGx) testing for germline DPYD and UGT1A1 variants associated with reduced enzyme activity holds the potential to identify… read more here.
Keywords: health; pgx testing; dpyd ugt1a1; chemotherapy ... See more keywords