Physicochemical and pharmacodynamic evaluation of pioglitazone binary systems with hydrophilic carriers
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2019.1616300
Abstract: Abstract Pioglitazone (PGZ) is an antidiabetic agent belongs to thiazolidinediones. Binary systems of PGZ in the matrices of kollicoat IR (KL) and gelucire (GL) at different weight ratios were prepared by kneading and co-evaporation methods,… read more here.
Keywords: pioglitazone; solid dispersion; diabetic control; binary systems ... See more keywords
Anticonvulsant and ameliorative effects of pioglitazone on cognitive deficits, inflammation and apoptosis in the hippocampus of rat pups exposed to febrile seizure
Sign Up to like & getrecommendations! Published in 2019 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2019.35056.8339
Abstract: Objective(s): Pioglitazone (PGZ), a peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist, has significant neuroprotective effects and has been reported to regulate inflammatory processes. Materials and Methods: We evaluated the effects of PGZ on febrile seizure (FS)… read more here.
Keywords: pgz; rat pups; cognitive deficits; seizure ... See more keywords
Nanostructured Lipid Carrier-Based Delivery of Pioglitazone for Treatment of Type 2 Diabetes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.934156
Abstract: Pioglitazone (PGZ) is utilized as a therapeutic agent in the management of (type 2) diabetes to control blood glucose levels. The existing research work was intended to make and optimize PGZ-containing NLCs (nanostructured lipid carriers).… read more here.
Keywords: nanostructured lipid; pgz nlcs; type diabetes; lipid carrier ... See more keywords