Articles with "ph009" as a keyword



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Abstract 4005: PH009-1, a highly potent and selective fourth-generation EGFR-TKI overcoming EGFR common mutations and T790M/C797S-mediated resistance in NSCLC

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-4005

Abstract: Background: Epidermal growth factor receptor (EGFR) activating mutations have been reported in 10-50% of patients with non-small cell lung cancer (NSCLC). The common mutations, ex19del (D) and L858R (L) substitution, are sensitive to first- and… read more here.

Keywords: common mutations; egfr tki; c797s; generation egfr ... See more keywords