Articles with "ph20" as a keyword



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The DNMT1-PAS1-PH20 axis drives breast cancer growth and metastasis

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Published in 2022 at "Signal Transduction and Targeted Therapy"

DOI: 10.1038/s41392-022-00896-1

Abstract: PH20 is a member of the human hyaluronidase family that degrades hyaluronan in the extracellular matrix and controls tumor progression. Inhibition of DNA methyltransferases (DNMTs) leads to elevated hyaluronan levels; however, whether DNMT inhibitors control… read more here.

Keywords: pas1; breast cancer; growth metastasis; ph20 ... See more keywords