Bacteriophage cocktail and phage antibiotic synergism as promising alternatives to conventional antibiotics for the control of multi-drug-resistant uropathogenic Escherichia coli.
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DOI: 10.1016/j.virusres.2021.198496
Abstract: Infections related to antibiotic resistant bacteria are accelerating on a global scale, and hence to encounter this problem in case of urinary tract infections; bacteriophages were isolated for biocontrol of multi-drug resistant (MDR) uropathogenic Escherichia… read more here.
Keywords: phage; drug resistant; cocktail; multi drug ... See more keywords
An Optimized Checkerboard Method for Phage-Antibiotic Synergy Detection
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DOI: 10.3390/v14071542
Abstract: Phage-antibiotic synergy is a promising therapeutic strategy, but there is no reliable method for synergism estimation. Although the time-kill curve assay is a gold standard, the method is not appropriate for fast and extensive screening… read more here.
Keywords: checkerboard method; phage antibiotic; antibiotic synergy; synergy ... See more keywords
Phage and Antibiotic Combinations Reduce Staphylococcus aureus in Static and Dynamic Biofilms Grown on an Implant Material
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DOI: 10.3390/v15020460
Abstract: Staphylococcus aureus causes the majority of implant-related infections. These infections present as biofilms, in which bacteria adhere to the surface of foreign materials and form robust communities that are resilient to the human immune system… read more here.
Keywords: dynamic biofilms; phage antibiotic; staphylococcus aureus; antibiotic combinations ... See more keywords
Short-Term Outcomes of Phage-Antibiotic Combination Treatment in Adult Patients with Periprosthetic Hip Joint Infection
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DOI: 10.3390/v15020499
Abstract: Implant-associated infections are the most costly problem in modern orthopedics due to the continued increase in the occurrence of antibiotic-resistant bacterial strains that requires the development of new effective antimicrobials. A non-randomized, prospective, open-label, with… read more here.
Keywords: hip joint; adult patients; phage antibiotic; joint infection ... See more keywords