Phage-Assisted Continuous Evolution and Selection of Enzymes for Chemical Synthesis
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DOI: 10.1021/acscentsci.1c00811
Abstract: Ligand-dependent biosensors are valuable tools for coupling the intracellular concentrations of small molecules to easily detectable readouts such as absorbance, fluorescence, or cell growth. While ligand-dependent biosensors are widely used for monitoring the production of… read more here.
Keywords: assisted continuous; evolution; phage; selection ... See more keywords
Phage-Assisted Continuous Evolution (PACE): A Guide Focused on Evolving Protein–DNA Interactions
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DOI: 10.1021/acsomega.0c03508
Abstract: The uptake of directed evolution methods is increasing, as these powerful systems can be utilized to develop new biomolecules with altered/novel activities, for example, proteins with new catalytic functions or substrate specificities and nucleic acids… read more here.
Keywords: protein; evolution; dna; pace ... See more keywords