Cell and Material-Specific Phage Display Peptides Increase iPS-MSC Mediated Bone and Vasculature Formation In Vivo.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201801356
Abstract: Biomimetically designed materials matching the chemical and mechanical properties of tissue support higher mesenchymal stem cell (MSC) adhesion. However, directing cell-specific attachment and ensuring uniform cell distribution within the interior of 3D biomaterials remain key… read more here.
Keywords: cell; formation vivo; phage display; vasculature ... See more keywords
Identification of a novel colon adenocarcinoma cell targeting peptide using phage display library biopanning
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.2320
Abstract: Phage display is well recognized as a promising high‐throughput screening tool for the discovery of novel cancer‐targeting peptides. Here, we screened a phage display library of 7‐mer random peptides through in vitro biopanning to isolate… read more here.
Keywords: display library; cell; phage display; colon ... See more keywords
Phage display as a tool to discover blood–brain barrier (BBB)‐shuttle peptides: panning against a human BBB cellular model
Sign Up to like & getrecommendations! Published in 2017 at "Peptide Science"
DOI: 10.1002/bip.22928
Abstract: Most potential drugs for the treatment of central nervous system disorders do not cross the blood–brain barrier (BBB). Much research effort has been devoted to the discovery of new BBB‐shuttle peptides—most of which have been… read more here.
Keywords: bbb shuttle; phage display; bbb; model ... See more keywords
Identification of peptide sequences that selectively bind to pentaerythritol trinitrate hemisuccinate‐a surrogate of PETN, via phage display technology
Sign Up to like & getrecommendations! Published in 2017 at "Peptide Science"
DOI: 10.1002/bip.22997
Abstract: The present research investigates the identification of amino acid sequences that selectively bind to a pentaerythritol tetranitrate (PETN) explosive surrogate. Through the use of a phage display technique and enzyme‐linked immunosorbent assays (ELISA), a peptide… read more here.
Keywords: sequences selectively; phage display; petn; surrogate ... See more keywords
Protein Chemical Synthesis Combined with Mirror‐Image Phage Display Yields d‐Peptide EGF Ligands that Block the EGF–EGFR Interaction
Sign Up to like & getrecommendations! Published in 2019 at "ChemBioChem"
DOI: 10.1002/cbic.201900355
Abstract: The epidermal growth factor (EGF) pathway, being overactive in a number of cancers, is a good target for clinical therapy. Although several drugs targeting the EGF receptor (EGFR) are on the market, tumours acquire resistance… read more here.
Keywords: egf egfr; egfr interaction; phage display;
Albumin domain mutants with enhanced Aβ binding capacity identified by phage display analysis for application in various peripheral Aβ elimination approaches of Alzheimer's disease treatment
Sign Up to like & getrecommendations! Published in 2019 at "IUBMB Life"
DOI: 10.1002/iub.2203
Abstract: Deposition of amyloid protein, particularly Aβ1‐42, is a major contributor to the onset of Alzheimer's disease (AD). However, almost no deposition of Aβ in the peripheral tissues could be found. Human serum albumin (HSA), the… read more here.
Keywords: binding capacity; phage display; alzheimer disease; phage ... See more keywords
Selection of a PD‐1 blocking antibody from a novel fully human phage display library
Sign Up to like & getrecommendations! Published in 2022 at "Protein Science"
DOI: 10.1002/pro.4486
Abstract: Programmed cell death protein 1 (PD‐1) is an immunoregulatory target which is recognized by different monoclonal antibodies, approved for the therapy of multiple types of cancer. Different anti‐PD‐1 antibodies display different therapeutic properties and there… read more here.
Keywords: selection blocking; blocking antibody; phage display; antibody ... See more keywords
Engineering sortase A by screening a second‐generation library using phage display
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Peptide Science"
DOI: 10.1002/psc.2980
Abstract: Sortase‐mediated ligation is one of the most commonly used chemo‐enzymatic techniques for the site‐specific modification of proteins. We have established a new library of sortase mutants for directed evolution of sortase substrate selectivity. Phage display… read more here.
Keywords: second generation; sortase; generation library; phage display ... See more keywords
Identification of PDZ Interactions by Proteomic Peptide Phage Display.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1166-1_3
Abstract: PSD95-Disc large-Zonula occludens (PDZ) domains are among the most abundant modular domains in the human proteome. They typically bind short carboxy-terminal sequence motifs of their ligand proteins, which may be transmembrane proteins such as ion… read more here.
Keywords: identification; peptide phage; pdz; phage display ... See more keywords
Large-Scale Interaction Profiling of Protein Domains Through Proteomic Peptide-Phage Display Using Custom Peptidomes.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6584-7_14
Abstract: Protein-protein interactions are essential to cellular functions and signaling pathways. We recently combined bioinformatics and custom oligonucleotide arrays to construct custom-made peptide-phage libraries for screening peptide-protein interactions, an approach we call proteomic peptide-phage display (ProP-PD).… read more here.
Keywords: protein; peptide phage; phage display; proteomic peptide ... See more keywords
Whole Cell Panning with Phage Display.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6857-2_5
Abstract: Phage display has emerged as one of the leading technologies for the selection of highly specific monoclonal antibodies, offering a number of advantages over traditional methods of antibody generation. While there are various possibilities to… read more here.
Keywords: cell; cell panning; whole cell; phage display ... See more keywords