A phage-encoded anti-activator inhibits quorum sensing in Pseudomonas aeruginosa.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular cell"
DOI: 10.1016/j.molcel.2020.12.011
Abstract: The arms race between bacteria and phages has led to the evolution of diverse anti-phage defenses, several of which are controlled by quorum-sensing pathways. In this work, we characterize a quorum-sensing anti-activator protein, Aqs1, found… read more here.
Keywords: anti activator; encoded anti; phage; phage encoded ... See more keywords
Sourcing Phage-Encoded Terminators Using ONT-cappable-seq for SynBio Applications in Pseudomonas
Sign Up to like & getrecommendations! Published in 2023 at "ACS Synthetic Biology"
DOI: 10.1021/acssynbio.3c00101
Abstract: Efficient transcriptional terminators are essential for the performance of genetic circuitry in microbial SynBio hosts. In recent years, several libraries of characterized strong terminators have become available for model organisms such as Escherichia coli. Conversely,… read more here.
Keywords: ont cappable; phage encoded; sourcing phage; synbio ... See more keywords
Characterizing the portability of phage-encoded homologous recombination proteins
Sign Up to like & getrecommendations! Published in 2021 at "Nature chemical biology"
DOI: 10.1038/s41589-020-00710-5
Abstract: Efficient genome editing methods are essential for biotechnology and fundamental research. Homologous recombination (HR) is the most versatile method of genome editing, but techniques that rely on host RecA-mediated pathways are inefficient and laborious. Phage-encoded… read more here.
Keywords: single stranded; portability; homologous recombination; phage encoded ... See more keywords
A phage-encoded nucleoid associated protein compacts both host and phage DNA and derepresses H-NS silencing.
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic acids research"
DOI: 10.1093/nar/gkab678
Abstract: Nucleoid Associated Proteins (NAPs) organize the bacterial chromosome within the nucleoid. The interaction of the NAP H-NS with DNA also represses specific host and xenogeneic genes. Previously, we showed that the bacteriophage T4 early protein… read more here.
Keywords: microscopy; motb; dna; phage ... See more keywords
Incidence and Effects of Acquisition of the Phage-Encoded ssa Superantigen Gene in Invasive Group A Streptococcus
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.685343
Abstract: The acquisition of the phage-encoded superantigen ssa by scarlet fever-associated group A Streptococcus (Streptococcus pyogenes, GAS) is found in North Asia. Nonetheless, the impact of acquiring ssa by GAS in invasive infections is unclear. This… read more here.
Keywords: ssa; group streptococcus; phage encoded; gas ... See more keywords
Phage-encoded carbohydrate-interacting proteins in the human gut
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1083208
Abstract: In the human gastrointestinal tract, the gut mucosa and the bacterial component of the microbiota interact and modulate each other to accomplish a variety of critical functions. These include digestion aid, maintenance of the mucosal… read more here.
Keywords: encoded carbohydrate; phage encoded; carbohydrate interacting; mucus ... See more keywords