Phage endolysins are adapted to specific hosts and are evolutionarily dynamic
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Biology"
DOI: 10.1371/journal.pbio.3001740
Abstract: Endolysins are produced by (bacterio)phages to rapidly degrade the bacterial cell wall and release new viral particles. Despite sharing a common function, endolysins present in phages that infect a specific bacterial species can be highly… read more here.
Keywords: specific hosts; phage endolysins; hosts evolutionarily; endolysins adapted ... See more keywords
Discovering the Potentials of Four Phage Endolysins to Combat Gram-Negative Infections
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.748718
Abstract: Endolysin-based therapeutics are promising antibacterial agents and can successfully supplement the existing antibacterial drugs array. It is specifically important in the case of Gram-negative pathogens, e.g., ESKAPE group bacteria, which includes Enterococcus faecium, Staphylococcus aureus,… read more here.
Keywords: potentials four; gram negative; gram; phage endolysins ... See more keywords