Genetically distant bacteriophages select for unique genomic changes in Enterococcus faecalis
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DOI: 10.1002/mbo3.1273
Abstract: The human microbiota harbors diverse bacterial and bacteriophage (phage) communities. Bacteria evolve to overcome phage infection, thereby driving phage evolution to counter bacterial resistance. Understanding how phages select for genetic alterations in medically relevant bacteria… read more here.
Keywords: genetically distant; infection; faecalis genome; phage infection ... See more keywords
Strand-specific RNA-Seq analysis provides first insight into transcriptome response of Vibrio alginolyticus to phage infection
Sign Up to like & getrecommendations! Published in 2017 at "Marine Genomics"
DOI: 10.1016/j.margen.2017.05.011
Abstract: Abstract RNA-Seq transcriptome analysis of bacteria during phage infection has been occasionally reported in last several years but little is known about how Vibrio bacteria respond to phage invasion on global transcriptome level. In the… read more here.
Keywords: phage infection; analysis; phage; infection ... See more keywords
Viral evolution: Phage infection strategies
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Microbiology"
DOI: 10.1038/nrmicro.2017.71
Abstract: Liver infection by Plasmodium spp. sporozoites is a crucial initial step in the life cycle of malaria parasites; however, the underlying molecular mechanisms are still poorly understood. Now, a new study provides molecular insights into… read more here.
Keywords: phage infection; viral evolution; evolution phage; infection ... See more keywords
Playing dead during phage infection
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Microbiology"
DOI: 10.1038/s41579-019-0226-1
Abstract: A recent study reports that Cas13 induces a state of dormancy in bacteria, which inhibits viral replication and the rise of CRISPR-resistant phages. read more here.
Keywords: phage infection; dead phage; microbiology; playing dead ... See more keywords
RetS Regulates Phage Infection in Pseudomonas aeruginosa via Modulating the GacS/GacA Two-Component System
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.00197-22
Abstract: Our knowledge on the molecular mechanisms behind bacterium-phage interactions remains limited. Our study reported that the complex multisensing regulatory networks RetS-GacS/GacA of Pseudomonas aeruginosa PAO1 play key roles in controlling phage infection. ABSTRACT In Pseudomonas… read more here.
Keywords: system; phage infection; gacs gaca; infection ... See more keywords
Expression of a Phage-Encoded Gp21 Protein Protects Pseudomonas aeruginosa against Phage Infection
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.01769-21
Abstract: The majority of the annotated phage genes are currently deposited as “hypothetical protein” with unknown function. Research has revealed that some phage proteins serve to inhibit or redirect the host intracellular processes for phage infection.… read more here.
Keywords: infection; phage; phage infection; gp21 ... See more keywords
Parallel Genomics Uncover Novel Enterococcal-Bacteriophage Interactions
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DOI: 10.1128/mbio.03120-19
Abstract: We lack fundamental understanding of how phage infection influences bacterial gene expression and, consequently, how bacterial responses to phage infection affect the assembly of polymicrobial communities. Using parallel genomic approaches, we have discovered novel transcriptional… read more here.
Keywords: transcriptomic profiling; profiling phage; phage; genomic approaches ... See more keywords
Quorum Sensing Promotes Phage Infection in Pseudomonas aeruginosa PAO1
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DOI: 10.1128/mbio.03174-21
Abstract: Phage resistance is a major limitation of phage therapy, and understanding the mechanisms by which bacteria block phage infection is critical for the successful application of phage therapy. In the present study, we found that… read more here.
Keywords: phage infection; aeruginosa pao1; infection; phage ... See more keywords
Pseudomonas aeruginosa Resists Phage Infection via Eavesdropping on Indole Signaling
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.03911-22
Abstract: Our finding is significant with respect to the study of the interactions between phage and host. Although the important roles of indole in bacterial physiology have been revealed, no direct examples of indole participating in… read more here.
Keywords: pseudomonas aeruginosa; physiology; phage infection; phage host ... See more keywords
The Burden of Survivors: How Can Phage Infection Impact Non-Infected Bacteria?
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032733
Abstract: The contemporary understanding of complex interactions in natural microbial communities and the numerous mechanisms of bacterial communication challenge the classical concept of bacteria as unicellular organisms. Microbial populations, especially those in densely populated habitats, appear… read more here.
Keywords: infection impact; burden survivors; impact non; phage infection ... See more keywords
Survival Strategies of Streptococcus pyogenes in Response to Phage Infection
Sign Up to like & getrecommendations! Published in 2021 at "Viruses"
DOI: 10.3390/v13040612
Abstract: Bacteriophages exert strong evolutionary pressure on their microbial hosts. In their lytic lifecycle, complete bacterial subpopulations are utilized as hosts for bacteriophage replication. However, during their lysogenic lifecycle, bacteriophages can integrate into the host chromosome… read more here.
Keywords: phage infection; streptococcus pyogenes; phage; infection ... See more keywords