Novel Phage Lysin Abp013 against Acinetobacter baumannii
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DOI: 10.3390/antibiotics11020169
Abstract: As antimicrobial resistance (AMR) continues to pose an ever-growing global health threat, propelling us into a post-antibiotic era, novel alternative therapeutic agents are urgently required. Lysins are bacteriophage-encoded peptidoglycan hydrolases that display great potential as… read more here.
Keywords: abp013 acinetobacter; lysin abp013; novel phage; phage lysin ... See more keywords
Improvement of the Antibacterial Activity of Phage Lysin-Derived Peptide P87 through Maximization of Physicochemical Properties and Assessment of Its Therapeutic Potential
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DOI: 10.3390/antibiotics11101448
Abstract: Phage lysins are a promising alternative to common antibiotic chemotherapy. However, they have been regarded as less effective against Gram-negative pathogens unless engineered, e.g., by fusing them to antimicrobial peptides (AMPs). AMPs themselves pose an… read more here.
Keywords: antibacterial activity; phage lysin; p87; activity ... See more keywords