Phage Therapy: Primer and Role in the Treatment of MDROs
Sign Up to like & getrecommendations! Published in 2020 at "Current Infectious Disease Reports"
DOI: 10.1007/s11908-020-00742-x
Abstract: Given increasing prevalence of multi-drug resistant organisms (MDROs), there is a significant interest in exploring non-antibiotic therapeutic options. We discuss basics of bacteriophage therapy (BT) and its role in the treatment of infections due to… read more here.
Keywords: primer role; phage therapy; therapy primer; treatment ... See more keywords
A Mathematical Model for Phage Therapy with Impulsive Phage Dose
Sign Up to like & getrecommendations! Published in 2020 at "Differential Equations and Dynamical Systems"
DOI: 10.1007/s12591-016-0303-0
Abstract: An impulsively perturbed differential equation model for phage therapy has been proposed and investigated. A constant phage dose which accounts for impulse, is assumed to be given to the species (that can be a human,… read more here.
Keywords: phage therapy; phage; model phage; phage dose ... See more keywords
The Potential Role for Phage Therapy for Genetic Modification of Cutaneous Diseases.
Sign Up to like & getrecommendations! Published in 2022 at "Clinics in dermatology"
DOI: 10.1016/j.clindermatol.2022.02.011
Abstract: Antimicrobial resistance has become increasingly common across the globe, claiming over 33,000 lives annually in Europe and 23,000 lives in the United States alone. The problem lies in trying to find potential solutions capable of… read more here.
Keywords: therapy genetic; role phage; potential role; phage therapy ... See more keywords
European regulatory aspects of phage therapy: magistral phage preparations.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in virology"
DOI: 10.1016/j.coviro.2021.11.005
Abstract: Bacteriophages (phages) are bacterial viruses, and have been used for more than a century to combat bacterial infections, particularly in Poland and in the former Soviet Union. The antimicrobial resistance crisis has triggered a renewed… read more here.
Keywords: phage therapy; regulatory aspects; european regulatory; phage ... See more keywords
Phage Therapy for treatment of virulent Klebsiella pneumoniae infection in mouse model.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2019.09.018
Abstract: Klebsiella pneumoniae is an important emerging pathogen of humans and animals which may lead to major clinical implications including mortality. Moreover the increased use of antibiotics has promoted emergence of carbapenem resistant strains and extended… read more here.
Keywords: phage; pneumoniae; phage therapy; mouse model ... See more keywords
Treatment of Wound Infections in a Mouse Model Using Zn2+-Releasing Phage Bound to Gold Nanorods
Sign Up to like & getrecommendations! Published in 2022 at "ACS Nano"
DOI: 10.1021/acsnano.2c00048
Abstract: Infections caused by drug-resistant bacteria, particularly gram-negative organisms, are increasingly difficult to treat using antibiotics. A potential alternative is ‘phage therapy’, in which phages infect and lyse the bacterial host. However, phage therapy poses serious… read more here.
Keywords: phage therapy; treatment wound; phage nanomaterial; treatment ... See more keywords
Controlled phage therapy by photothermal ablation of specific bacterial species using gold nanorods targeted by chimeric phages
Sign Up to like & getrecommendations! Published in 2020 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1913234117
Abstract: Significance New methods for detecting and killing antibiotic-resistant, Gram-negative bacteria are of prime interest for a wide variety of applications. While phages have long been considered as potential antibacterial agents, many concerns about phage therapy… read more here.
Keywords: gold nanorods; phage therapy; biology; ablation ... See more keywords
Compassionate Use of Bacteriophages for Failed Persistent Infections During the First 5 Years of the Israeli Phage Therapy Center
Sign Up to like & getrecommendations! Published in 2023 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofad221
Abstract: Abstract The use of bacteriophages (phages) is reemerging as a potential treatment option for antibiotic-resistant or nonresolving bacterial infections. Phages are bacteria-specific viruses that may serve as a personalized therapeutic option with minimal collateral damage… read more here.
Keywords: israeli phage; phage therapy; center; use ... See more keywords
A phage therapy model for the prevention of Pseudomonas syringae pv. actinidiae infection of kiwifruit plants.
Sign Up to like & getrecommendations! Published in 2022 at "Plant disease"
DOI: 10.1094/pdis-02-22-0348-sc
Abstract: Great efforts have been made with chemicals and pesticides to contain the spread of Pseudomonas syringae pv. actinidiae (Psa) responsible for kiwifruit canker. Unfortunately, only partial results were obtained for this bacterial pandemic and alternative… read more here.
Keywords: syringae actinidiae; phage therapy; kiwifruit; pseudomonas syringae ... See more keywords
Role of bacteriophage therapy for resistant infections in transplant recipients
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Organ Transplantation"
DOI: 10.1097/mot.0000000000001029
Abstract: Purpose of review Multidrug-resistant organisms (MDROs) are prevalent in transplant recipients and associated with poor outcomes. We review recent cases of phage therapy used to treat recalcitrant infections in transplant recipients and explore the future… read more here.
Keywords: phage therapy; role bacteriophage; therapy; transplant recipients ... See more keywords
Battling Superbugs: How Phage Therapy Went From Obscure to Promising
Sign Up to like & getrecommendations! Published in 2019 at "IEEE Pulse"
DOI: 10.1109/mpuls.2018.2885833
Abstract: Until a dangerous bacterial infection left her husband near death 3 years ago, scientist Steffanie Strathdee had never heard of bacteriophage therapy. After it ultimately saved his life, however, she not only has become a… read more here.
Keywords: therapy; superbugs phage; battling superbugs; therapy went ... See more keywords