HIV-1 Tat disrupts blood-brain barrier integrity and increases phagocytic perivascular macrophages and microglia in the dorsal striatum of transgenic mice
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DOI: 10.1016/j.neulet.2016.12.073
Abstract: HIV-1 infection results in blood-brain barrier (BBB) disruption, which acts as a rate-limiting step for HIV-1 entry into the CNS and for subsequent neuroinflammatory/neurotoxic actions. One mechanism by which HIV may destabilize the BBB involves… read more here.
Keywords: phagocytic perivascular; macrophages microglia; hiv tat; perivascular macrophages ... See more keywords