Anaplasma phagocytophilum infection modulates expression of megakaryocyte cell cycle genes through phosphatidylinositol-3-kinase signaling
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DOI: 10.1371/journal.pone.0182898
Abstract: Anaplasma phagocytophilum, the agent of human granulocytic anaplasmosis infects neutrophils and other cells from hematopoietic origin. Using human megakaryocytic cell line, MEG-01, we show that expression of cell cycle genes in these cells are altered… read more here.
Keywords: phagocytophilum infection; cycle genes; cell; cell cycle ... See more keywords
Anaplasma phagocytophilum Infection Subverts Carbohydrate Metabolic Pathways in the Tick Vector, Ixodes scapularis
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DOI: 10.3389/fcimb.2017.00023
Abstract: The obligate intracellular pathogen, Anaplasma phagocytophilum, is the causative agent of human, equine, and canine granulocytic anaplasmosis and tick-borne fever (TBF) in ruminants. A. phagocytophilum has become an emerging tick-borne pathogen in the United States,… read more here.
Keywords: phagocytophilum infection; metabolic pathways; major carbohydrate; carbohydrate metabolic ... See more keywords
Vaccinomics Approach to the Identification of Candidate Protective Antigens for the Control of Tick Vector Infestations and Anaplasma phagocytophilum Infection
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DOI: 10.3389/fcimb.2017.00360
Abstract: Anaplasma phagocytophilum is an emerging tick-borne pathogen causing human granulocytic anaplasmosis (HGA), tick-borne fever (TBF) in small ruminants, and other forms of anaplasmosis in different domestic and wild animals. The main vectors of this pathogen… read more here.
Keywords: control; candidate; infection; phagocytophilum infection ... See more keywords