Microglial phagocytosis dysfunction in stroke is driven by energy depletion and induction of autophagy.
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DOI: 10.1080/15548627.2023.2165313
Abstract: Microglial phagocytosis of apoptotic debris prevents buildup damage of neighbor neurons and inflammatory responses. Whereas microglia are very competent phagocytes under physiological conditions, we report their dysfunction in mouse and preclinical monkey models of stroke… read more here.
Keywords: phagocytosis; microglial phagocytosis; dysfunction; phagocytosis dysfunction ... See more keywords