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Phagocytosis of Erythrocytes from Gaucher Patients Induces Phenotypic Modifications in Macrophages, Driving Them toward Gaucher Cells

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23147640

Abstract: Gaucher disease (GD) is caused by glucocerebrosidase deficiency leading to the accumulation of sphingolipids in macrophages named “Gaucher’s Cells”. These cells are characterized by deregulated expression of cell surface markers, abnormal secretion of inflammatory cytokines,… read more here.

Keywords: gaucher patients; gaucher cells; gaucher; phagocytosis erythrocytes ... See more keywords