Quantitative Spatiotemporal Analysis of Phagosome Maturation in Live Cells.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6581-6_11
Abstract: Phagocytosis and phagosome maturation are central to the development of the innate and adaptive immune response. Phagosome maturation is a continuous and dynamic process that occurs rapidly. In this chapter, we describe fluorescence-based live cell… read more here.
Keywords: spatiotemporal analysis; quantitative spatiotemporal; analysis phagosome; phagosome maturation ... See more keywords
Phagosome maturation in macrophages: Eat, digest, adapt, and repeat.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in biological regulation"
DOI: 10.1016/j.jbior.2021.100832
Abstract: Phagocytosis is a dynamic process that requires an intricate interplay between phagocytic receptors, membrane lipids, and numerous signalling proteins and their effectors, to coordinate the engulfment of a bound particle. These particles are diverse in… read more here.
Keywords: phagosome maturation; eat digest; digest adapt; maturation ... See more keywords
Spleen-based proteogenomics reveals that Escherichia coli infection induces activation of phagosome maturation pathway in chicken
Sign Up to like & getrecommendations! Published in 2022 at "Virulence"
DOI: 10.1080/21505594.2022.2150453
Abstract: ABSTRACT Avian pathogenic Escherichia coli (APEC) leads to economic losses in poultry industry and is also a threat to human health. Various strategies were used for searching virulence factors, while little is known about the… read more here.
Keywords: coli infection; escherichia coli; infection; maturation pathway ... See more keywords
The SapM phosphatase can arrest phagosome maturation in an ESX-1 independent manner in Mycobacterium tuberculosis and BCG
Sign Up to like & getrecommendations! Published in 2024 at "Infection and Immunity"
DOI: 10.1128/iai.00217-24
Abstract: ABSTRACT Mycobacterium tuberculosis (Mtb) is an intracellular pathogen that survives and grows in macrophages. A mechanism used by Mtb to achieve intracellular survival is to secrete effector molecules that arrest the normal process of phagosome… read more here.
Keywords: bcg; pma; sapm; mtb ... See more keywords
Mycobacterium tuberculosis Utilizes Host Histamine Receptor H1 to Modulate Reactive Oxygen Species Production and Phagosome Maturation via the p38MAPK-NOX2 Axis
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DOI: 10.1128/mbio.02004-22
Abstract: Once engulfed in macrophage phagosomes, M. tuberculosis adopts various strategies to take advantage of the host environment for its intracellular survival. Histamine is an organic nitrogen-containing compound that mediates a plethora of cellular processes via… read more here.
Keywords: tuberculosis; phagosome maturation; production; mechanism ... See more keywords
IRAP Endosomes Control Phagosomal Maturation in Dendritic Cells
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.585713
Abstract: Dendritic cells (DCs) contribute to the immune surveillance by sampling their environment through phagocytosis and endocytosis. We have previously reported that, rapidly following uptake of extracellular antigen into phagosomes or endosomes in DCs, a specialized… read more here.
Keywords: phagosome maturation; cross presentation; irap; dendritic cells ... See more keywords
Leishmania braziliensis: Strain-Specific Modulation of Phagosome Maturation
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2019.00319
Abstract: Leishmania (Viannia) braziliensis is responsible for the largest number of American tegumentary leishmaniasis (ATL) in Brazil. ATL can present several clinical forms including typical (TL) and atypical (AL) cutaneous and mucocutaneous (ML) lesions. To identify… read more here.
Keywords: leishmania braziliensis; phagosome maturation; braziliensis; strain specific ... See more keywords
Examining the Underappreciated Role of S-Acylated Proteins as Critical Regulators of Phagocytosis and Phagosome Maturation in Macrophages
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.659533
Abstract: Phagocytosis is a receptor-mediated process used by cells to engulf a wide variety of particulates, including microorganisms and apoptotic cells. Many of the proteins involved in this highly orchestrated process are post-translationally modified with lipids… read more here.
Keywords: phagosome maturation; acylated proteins; phagocytosis phagosome; underappreciated role ... See more keywords