Theophylline-nicotinamide pharmaceutical co-crystals generated using hot melt extrusion technology: Impact of polymeric carriers on processability.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of drug delivery science and technology"
DOI: 10.1016/j.jddst.2020.102128
Abstract: The objective of the current study was to develop theophylline (TPH) nicotinamide (NAM) pharmaceutical co-crystals using the hot melt extrusion (HME) technology and evaluate the processability of the co-crystals using different polymeric carriers. A physical… read more here.
Keywords: polymeric carriers; using hot; pharmaceutical crystals; technology ... See more keywords
Multicomponent crystals of anti-tuberculosis drugs: a mini-review
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DOI: 10.1039/d0ra06478e
Abstract: Tuberculosis (TB) is the leading cause of death from a single infectious agent globally. Some of the early research on TB treatment indicated drug resistance as one of the key challenges in fighting this disease.… read more here.
Keywords: multicomponent crystals; active pharmaceutical; drug; tuberculosis ... See more keywords
Stability of Pharmaceutical Co-Crystals at Humid Conditions Can Be Predicted
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DOI: 10.3390/pharmaceutics13030433
Abstract: Knowledge of the stability of pharmaceutical formulations against relative humidity (RH) is essential if they are to become pharmaceutical products. The increasing interest in formulating active pharmaceutical ingredients as stable co-crystals (CCs) triggers the need… read more here.
Keywords: crystals humid; pharmaceutical crystals; stability pharmaceutical; humid conditions ... See more keywords