Poly(amidoamine) Dendrimers as a Pharmaceutical Excipient. Are We There yet?
Sign Up to like & getrecommendations! Published in 2018 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2017.10.011
Abstract: Drug solubility could affect the therapeutic use of a drug because the biological activity of a drug is only possible if some fraction of a dissolved drug can permeate and overcome biological membranes to reach… read more here.
Keywords: pharmaceutical excipient; drug; solubilization; poly amidoamine ... See more keywords
The Biological Fate of Pharmaceutical Excipient β-Cyclodextrin: Pharmacokinetics, Tissue Distribution, Excretion, and Metabolism of β-Cyclodextrin in Rats
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DOI: 10.3390/molecules27031138
Abstract: β-cyclodextrin has a unique annular hollow ultrastructure that allows encapsulation of various poorly water-soluble drugs in the resulting cavity, thereby increasing drug stability. As a bioactive molecule, the metabolism of β-cyclodextrin is mainly completed by… read more here.
Keywords: pharmaceutical excipient; metabolism cyclodextrin; excipient cyclodextrin; excretion ... See more keywords