Making fine chemicals, nanomaterials and pharmaceutical ingredients over SiliaCat catalysts
Sign Up to like & getrecommendations! Published in 2020 at "Applied Materials Today"
DOI: 10.1016/j.apmt.2020.100661
Abstract: Abstract Referring to selected independent research achievements using sol-gel organosilica catalysts of the SiliaCat series to make fine chemicals, nanomaterials and active pharmaceutical ingredients, we suggest avenues to incorporate these and related sol-gel catalytic materials… read more here.
Keywords: making fine; chemicals nanomaterials; fine chemicals; nanomaterials pharmaceutical ... See more keywords
Fate of active pharmaceutical ingredients in a northern high-rate algal pond fed with municipal wastewater.
Sign Up to like & getrecommendations! Published in 2021 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2021.129763
Abstract: Active pharmaceutical ingredients (APIs) are vital to human health and welfare, but following therapeutic use, they may pose a potential ecological risk if discharged into the environment. Today's conventional municipal wastewater treatment plants are not… read more here.
Keywords: active pharmaceutical; wastewater; high rate; municipal wastewater ... See more keywords
The influence of polymeric excipients on desupersaturation profiles of active pharmaceutical ingredients. 1: Polyethylene glycol.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.119317
Abstract: Polymeric excipients have proven to be beneficial in stabilizing supersaturated solutions of poorly soluble active pharmaceutical ingredients (APIs). They are therefore considered an important tool in improving oral bioavailability of such APIs. To better understand… read more here.
Keywords: crystal growth; active pharmaceutical; polymeric excipients; desupersaturation ... See more keywords
Atomic Force Microscopy to Identify Dehydration Temperatures for Small Volumes of Active Pharmaceutical Ingredients.
Sign Up to like & getrecommendations! Published in 2020 at "Powder technology"
DOI: 10.1016/j.powtec.2019.09.045
Abstract: The environmental conditions associated with changing the hydration state of active pharmaceutical ingredients (API) are crucial to understanding their stability, bioperformance, and manufacturability. Identifying the dehydration event using < 1μg of material is an increasingly… read more here.
Keywords: microscopy; force microscopy; active pharmaceutical; atomic force ... See more keywords
Technoeconomic Optimization of Continuous Crystallization for Three Active Pharmaceutical Ingredients: Cyclosporine, Paracetamol, and Aliskiren
Sign Up to like & getrecommendations! Published in 2018 at "Industrial & Engineering Chemistry Research"
DOI: 10.1021/acs.iecr.8b00679
Abstract: Mixed suspension, mixed product removal (MSMPR) crystallizers are widely implemented for the continuous crystallization of active pharmaceutical ingredients (APIs), allowing enhanced efficiency, flexibility, and product quality compared to currently dominant batch crystallizer designs. Establishing cost-effective… read more here.
Keywords: crystallization; active pharmaceutical; optimization; cyclosporine paracetamol ... See more keywords
Mechanochemistry for “no solvent, no base” preparation of hydantoin-based active pharmaceutical ingredients: nitrofurantoin and dantrolene
Sign Up to like & getrecommendations! Published in 2018 at "Green Chemistry"
DOI: 10.1039/c8gc01345d
Abstract: The eco-compatible, base- and waste-free, energy-efficient, low-environmental-impact, gram-scale, mechanochemical preparation of marketed drugs such as nitrofurantoin (Furantin©), dantrolene (Dantrium©) and their structurally related derivatives is herein reported. Not a drop of organic solvent was used… read more here.
Keywords: active pharmaceutical; mechanochemistry solvent; solvent base; preparation ... See more keywords
Continuous flow upgrading of glycerol toward oxiranes and active pharmaceutical ingredients thereof
Sign Up to like & getrecommendations! Published in 2019 at "Green Chemistry"
DOI: 10.1039/c9gc01819k
Abstract: A robust continuous flow procedure for the transformation of bio-based glycerol into high value-added β-amino alcohol active pharmaceutical ingredients. read more here.
Keywords: active pharmaceutical; flow upgrading; continuous flow; pharmaceutical ingredients ... See more keywords
Multicomponent crystals of anti-tuberculosis drugs: a mini-review
Sign Up to like & getrecommendations! Published in 2020 at "RSC Advances"
DOI: 10.1039/d0ra06478e
Abstract: Tuberculosis (TB) is the leading cause of death from a single infectious agent globally. Some of the early research on TB treatment indicated drug resistance as one of the key challenges in fighting this disease.… read more here.
Keywords: multicomponent crystals; active pharmaceutical; drug; tuberculosis ... See more keywords
Production of active pharmaceutical ingredients (APIs) from lignin-derived phenol and catechol
Sign Up to like & getrecommendations! Published in 2021 at "Green Chemistry"
DOI: 10.1039/d1gc02158c
Abstract: Active pharmaceutical ingredients (APIs) constitute a significant and growing global market; renewables are an increasingly important source of their starting materials. read more here.
Keywords: lignin derived; active pharmaceutical; production active; ingredients apis ... See more keywords
Biocatalysis for the asymmetric synthesis of Active Pharmaceutical Ingredients (APIs): this time is for real
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2022.2114453
Abstract: ABSTRACT Introduction Biocatalysis has emerged as a powerful and useful strategy for the synthesis of active pharmaceutical ingredients (APIs). The outstanding developments in molecular biology techniques allow nowadays the screening, large-scale production, and designing of… read more here.
Keywords: synthesis active; active pharmaceutical; ingredients apis; pharmaceutical ingredients ... See more keywords
Modifying release of poorly soluble active pharmaceutical ingredients with the amine functionalized SBA-16 type mesoporous materials
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biomaterials Applications"
DOI: 10.1177/0885328219830823
Abstract: SBA-16 and two modified SBA-16 type ordered mesoporous silica were used as the carriers for ibuprofen (anti-inflammatory drug) and furosemide (loop diuretic drug). Modification of the solid carrier was prepared with chitosan or N-3[(amino(poly-propylenoxy)]aminopropyltrimethoxysilane. The… read more here.
Keywords: mesoporous materials; active pharmaceutical; sba type; pharmaceutical ingredients ... See more keywords