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Published in 2017 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2017.01.007
Abstract: HIGHLIGHTSHPLC Separation of enantiomers of four 3‐aryl‐substituted‐&ggr;‐butyrolactones (3AGBL).ECD, ORD, and VCD of four 3AGBL. Similarity indexes calculated for VCD and ECD.From AD‐H columns (S) enantiomers of 3AGBL elute before (R) enantiomers.Molecular Docking explains elution order.Lactone‐chirality…
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Keywords:
substituted ggr;
pharmaceutical interest;
aryl substituted;
key intermediates ... See more keywords