Immunomodulatory effects of pharmaceutical opioids and antipyretic analgesics: Mechanisms and relevance to infection
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DOI: 10.1111/bcp.15281
Abstract: Understanding how pharmaceutical opioids and antipyretic analgesics interact with the immune system potentially has major clinical implications for management of patients with infectious diseases and surgical and critical care patients. An electronic search was carried… read more here.
Keywords: antipyretic analgesics; opioids antipyretic; infection; immunity ... See more keywords
Investigating Endogenous Opioids Unravels the Mechanisms Behind Opioid-Induced Constipation, a Mathematical Modeling Approach
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DOI: 10.3390/ijms26136207
Abstract: Endogenous opioids, such as Endomorphin-2, are not typically associated with severe constipation, unlike pharmaceutical opioids, which induce opioid-induced constipation (OIC) by activating μ-opioid receptors in the gastrointestinal tract. In this study, we present a mathematical… read more here.
Keywords: endogenous opioids; pharmaceutical opioids; constipation; opioid induced ... See more keywords
Interventions for reducing the prescribing of pharmaceutical opioids in Australia: are they effectively reducing opioid harm?
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DOI: 10.5694/mja2.52259
Abstract: n response to concerns about prescription opioid overuse and related harms, a series of interventions to control their supply have been undertaken in Australia. In the analysis reported in this issue of the MJA ,… read more here.
Keywords: opioids australia; australia effectively; pharmaceutical opioids; prescribing pharmaceutical ... See more keywords