Towards the Institutionalization of Quantum Computing in Pharmaceutical Research.
Sign Up to like & getrecommendations! Published in 2021 at "Drug discovery today"
DOI: 10.1016/j.drudis.2021.10.006
Abstract: Innovative pharmaceutical companies have started to explore quantum computing ('QC'). In this article we provide a collective industry perspective from QC domain leaders at leading pharmaceutical companies. There are immediate non-financial benefits in engaging with… read more here.
Keywords: pharmaceutical research; quantum computing; drug; institutionalization quantum ... See more keywords
Enhanced Sensitivity Using MALDI Imaging Coupled with Laser Postionization (MALDI-2) for Pharmaceutical Research
Sign Up to like & getrecommendations! Published in 2019 at "Analytical Chemistry"
DOI: 10.1021/acs.analchem.9b02495
Abstract: Visualizing the distributions of drugs and their metabolites is one of the key emerging application areas of matrix-assisted laser desorption/ionization–mass spectrometry imaging (MALDI-MSI) within pharmaceutical research. The success of a given MALDI-MSI experiment is ultimately… read more here.
Keywords: using maldi; pharmaceutical research; ionization; laser ... See more keywords
Can quantitative pharmacology improve productivity in pharmaceutical research and development?
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2020.1776257
Abstract: Average R&D productivity in the pharmaceutical industry is less than 5% from the conception of idea to registration. Despite an increase in FDA-approved new drugs in the last 5Â years (247 between 2... read more here.
Keywords: pharmaceutical research; improve productivity; pharmacology; pharmacology improve ... See more keywords
Commentary: Reconsidering Pharmaceutical Research and Development Investments
Sign Up to like & getrecommendations! Published in 2023 at "Healthcare Policy"
DOI: 10.12927/hcpol.2023.27037
Abstract: Following Lee and colleagues' (2023) article explaining how Canadians are being shortchanged by drug companies when it comes to investments in research and development (R&D), this rejoinder adds context and appends two other very problematic… read more here.
Keywords: reconsidering pharmaceutical; research development; commentary reconsidering; pharmaceutical research ... See more keywords
State-of-the-art Application of Artificial Intelligence to Transporter-centered Functional and Pharmaceutical Research.
Sign Up to like & getrecommendations! Published in 2023 at "Current drug metabolism"
DOI: 10.2174/1389200224666230523155759
Abstract: Protein transporters not only have essential functions in regulating the transport of endogenous substrates and remote communication between organs and organisms, but they also play a vital role in drug absorption, distribution, and excretion and… read more here.
Keywords: transporter; artificial intelligence; pharmaceutical research; functional pharmaceutical ... See more keywords