Pharmacodynamic evaluation of novel Catechol‐O‐methyltransferase inhibitors
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2019.01.027
Abstract: ABSTRACT Currently, peripheral COMT inhibitors have an important role in the treatment of Parkinson's disease, and central COMT inhibitors have a potential role in the treatment of various neuropsychiatric disorders, such as attention deficit hyperactivity… read more here.
Keywords: evaluation novel; comt inhibitors; comt; pharmacodynamic evaluation ... See more keywords
884: PHARMACOKINETIC AND PHARMACODYNAMIC EVALUATION OF LEVETIRACETAM IN CRITICALLY ILL PATIENTS WITH SAH
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DOI: 10.1097/01.ccm.0000631672.09389.23
Abstract: Introduction/Hypothesis: Levetiracetam is frequently utilized as seizure prophylaxis due to its favorable side effect profile compared to other antiepileptic drugs. Levetiracetam is renally eliminated through glomerular filtration and exhibits linear pharmacokinetics. A recent pharmacokinetic study… read more here.
Keywords: pharmacokinetic pharmacodynamic; pharmacodynamic evaluation; day; clearance ... See more keywords
Physiologically based pharmacokinetic‐pharmacodynamic evaluation of meropenem plus fosfomycin in paediatrics
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DOI: 10.1111/bcp.14456
Abstract: The objective of the current study was to evaluate paediatric dosing regimens for meropenem plus fosfomycin that generate sufficient coverage against multidrug‐resistant bacteria. read more here.
Keywords: based pharmacokinetic; physiologically based; plus fosfomycin; pharmacokinetic pharmacodynamic ... See more keywords
Pharmacokinetic / Pharmacodynamic Evaluation of Marbofloxacin for Common Pathogens in Swine Following Single Intramuscular Administration of Different Doses
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DOI: 10.29261/pakvetj/2018.046
Abstract: Received: Revised: Accepted: Published online: September 12, 2017 November 25, 2017 January 10, 2018 April 17, 2018 The aims of the present work were to study the pharmacokinetics of marbofloxacin 10% solution after single i.m.… read more here.
Keywords: administration; common pathogens; pharmacokinetic pharmacodynamic; pharmacodynamic evaluation ... See more keywords
Pharmacokinetic/Pharmacodynamic Evaluation of a New Purine-2,6-Dione Derivative in Rodents with Experimental Autoimmune Diseases
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DOI: 10.3390/pharmaceutics14051090
Abstract: Current treatment strategies of autoimmune diseases (ADs) display a limited efficacy and cause numerous adverse effects. Phosphodiesterase (PDE)4 and PDE7 inhibitors have been studied recently as a potential treatment of a variety of ADs. In… read more here.
Keywords: new purine; compound; evaluation new; autoimmune diseases ... See more keywords