Clinical Pharmacokinetic and Pharmacodynamic Profile of Riociguat
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DOI: 10.1007/s40262-017-0604-7
Abstract: Oral riociguat is a soluble guanylate cyclase (sGC) stimulator that targets the nitric oxide (NO)–sGC–cyclic guanosine monophosphate pathway with a dual mode of action: directly by stimulating sGC, and indirectly by increasing the sensitivity of… read more here.
Keywords: pharmacodynamic profile; profile riociguat; sgc; pharmacokinetic pharmacodynamic ... See more keywords
Temporin B Forms Hetero-Oligomers with Temporin L, Modifies Its Membrane Activity, and Increases the Cooperativity of Its Antibacterial Pharmacodynamic Profile
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DOI: 10.1021/acs.biochem.1c00762
Abstract: The pharmacodynamic profile of antimicrobial peptides (AMPs) and their in vivo synergy are two factors that are thought to restrict resistance evolution and ensure their conservation. The frog Rana temporaria secretes a family of closely… read more here.
Keywords: temporin forms; activity; temporin; pharmacodynamic profile ... See more keywords
Pharmacokinetic and pharmacodynamic profile of the sodium‐glucose co‐transporter‐2 inhibitor empagliflozin in young people with Type 2 diabetes: a randomized trial
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DOI: 10.1111/dme.13629
Abstract: To assess the pharmacokinetic and pharmacodynamic profile of a single dose of empagliflozin in young people with Type 2 diabetes to identify the appropriate doses for further paediatric development. read more here.
Keywords: pharmacodynamic profile; people type; empagliflozin young; type diabetes ... See more keywords