Proniosomal gel-derived niosomes: an approach to sustain and improve the ocular delivery of brimonidine tartrate; formulation, in-vitro characterization, and in-vivo pharmacodynamic study
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DOI: 10.1080/10717544.2019.1609622
Abstract: Abstract Brimonidine tartrate (BRT) is a hydrophilic α2 adrenergic agonist used for the treatment of glaucoma. Glaucoma is an ocular disease affecting the anterior segment of the eye requiring lifetime treatment. Owing to the obstacles… read more here.
Keywords: improve ocular; delivery; vivo pharmacodynamic; brimonidine tartrate ... See more keywords
In vivo pharmacokinetic and pharmacodynamic study of co-spray-dried inhalable pirfenidone microparticles in rats
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DOI: 10.1080/10717544.2022.2149899
Abstract: Abstract Pirfenidone (PRF) is the first FDA-approved API in the treatment of idiopathic pulmonary fibrosis (IPF). However, PRF induces serious side effects, such as photophobia and gastrointestinal disorder. PRF inhalation can be expected with a… read more here.
Keywords: spray; pharmacodynamic study; spray dried; pharmacokinetic pharmacodynamic ... See more keywords
Comparison of classical, stealth and super-stealth liposomes for intravenous delivery of lumefantrine: Formulation, characterization and pharmacodynamic study
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DOI: 10.4314/tjpr.v19i11.1
Abstract: Purpose: To develop and compare classical liposomes (CL), stealth liposomes (SL) and super-stealth liposomes (SSL) encapsulating lumefantrine for intravenous administration. Method: CL, SL or SSL were prepared by thin-layer evaporation method and evaluated for particle… read more here.
Keywords: stealth liposomes; lumefantrine; stealth; pharmacodynamic study ... See more keywords