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Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24108538
Abstract: Systemic sclerosis (SSc) is a rare connective tissue disorder with highest morbidity and mortality among rheumatologic diseases. Disease progression is highly heterogeneous between patients, implying a strong need for individualization of therapy. Four pharmacogenetic variants,…
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Keywords:
systemic sclerosis;
patients ssc;
pharmacogenetic variants;
slco1b1 ... See more keywords
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Published in 2021 at "PeerJ"
DOI: 10.7717/peerj.11774
Abstract: Background Pharmacogenetic variation is important to drug responses through diverse and complex mechanisms. Predictions of the functional impact of missense pharmacogenetic variants primarily rely on the degree of sequence conservation between species as a primary…
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Keywords:
predictions functional;
pharmacogenetic variants;
target;
drug ... See more keywords