Pharmacogenomic studies of fertility outcomes in pediatric cancer survivors – A systematic review
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DOI: 10.1111/cts.13827
Abstract: For the same age, sex, and dosage, there can be significant variation in fertility outcomes in childhood cancer survivors. Genetics may explain this variation. This study aims to: (i) review the genetic contributions to infertility,… read more here.
Keywords: cancer; cancer survivors; pharmacogenomic studies; fertility ... See more keywords
Quantifying Sample Representation in Global Pharmacogenomic Studies of Major Depressive Disorder: A Systematic Review
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DOI: 10.1111/cts.70256
Abstract: ABSTRACT Major depressive disorder (MDD) is a substantial public health challenge. Pharmacogenomics (PGx), which identifies genetic variations that predict drug treatment outcomes, may have utility for clinical practice, but adequate representation of all populations is… read more here.
Keywords: depressive disorder; pharmacogenomic studies; systematic review; representation ... See more keywords
O-41 Pharmacogenomic studies of corticosteroid effectiveness in paediatric asthma: a systematic review
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DOI: 10.1136/archdischild-2017-esdppp.41
Abstract: Background Genetic variations has the potential to al-ter therapeutic efficacy. The aim of the study is to analyse polymorphisms associated with variation in response to corticosteroid treatment in paediatric asthma patients. Asthma is one of… read more here.
Keywords: corticosteroid effectiveness; studies corticosteroid; pharmacogenomic studies; asthma ... See more keywords