Clinically actionable genotypes for anticancer prescribing among >1500 patients with pharmacogenomic testing
Sign Up to like & getrecommendations! Published in 2022 at "Cancer"
DOI: 10.1002/cncr.34104
Abstract: In recent years, there has been increasing evidence supporting the role of germline pharmacogenomic factors predicting toxicity for anticancer therapies. Although somatic genomic data are used frequently in oncology care planning, germline pharmacogenomic testing is… read more here.
Keywords: actionable genotypes; clinically actionable; pharmacogenomic testing; genotypes anticancer ... See more keywords
A retrospective analysis of preemptive pharmacogenomic testing in 22,918 individuals from China
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24855
Abstract: Pharmacogenomics (PGx) examines the influence of genetic variation on drug responses. With more and more Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines published, PGx is gradually shifting from the reactive testing of single gene toward the… read more here.
Keywords: pharmacogenomic testing; preemptive pharmacogenomic; analysis; analysis preemptive ... See more keywords
Pharmacogenomic Testing in Child and Adolescent Psychiatry: An Evidence-Based Review.
Sign Up to like & getrecommendations! Published in 2018 at "Current problems in pediatric and adolescent health care"
DOI: 10.1016/j.cppeds.2017.12.003
Abstract: Significant advances have been made in the application of pharmacogenomic testing for the treatment of patients with psychiatric disorders. Over the past decade, a number of studies have evaluated the utility of pharmacogenomic testing in… read more here.
Keywords: pharmacogenomic testing; evidence; testing child; medication ... See more keywords
Prescription patterns of outpatients and the potential of multiplexed pharmacogenomic testing
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.14439
Abstract: Pre‐emptive pharmacogenomic (PGx) testing is potentially an efficient approach to improve drug safety and efficacy but the target population to test is unclear. read more here.
Keywords: pharmacogenomic testing; potential multiplexed; outpatients potential; multiplexed pharmacogenomic ... See more keywords
Advancing Pharmacogenomics from Single-Gene to Preemptive Testing.
Sign Up to like & getrecommendations! Published in 2022 at "Annual review of genomics and human genetics"
DOI: 10.1146/annurev-genom-111621-102737
Abstract: Pharmacogenomic testing can be an effective tool to enhance medication safety and efficacy. Pharmacogenomically actionable medications are widely used, and approximately 90-95% of individuals have an actionable genotype for at least one pharmacogene. For pharmacogenomic… read more here.
Keywords: advancing pharmacogenomics; pharmacogenomic testing; preemptive testing; pharmacogenomics single ... See more keywords
Pharmacogenomic testing and its future in community pharmacy
Sign Up to like & getrecommendations! Published in 2020 at "Polymer Journal"
DOI: 10.1211/pj.2019.20207342
Abstract: Although it is common to see pharmacogenomic testing used North America and Australia, it is not yet part of practice in the UK. With the promise of genomic screening becoming part of the NHS, pharmacists… read more here.
Keywords: medicine; future community; testing future; pharmacogenomic testing ... See more keywords
Pharmacogenomic Testing In Pediatrics: Navigating The Ethical, Social, And Legal Challenges
Sign Up to like & getrecommendations! Published in 2019 at "Pharmacogenomics and Personalized Medicine"
DOI: 10.2147/pgpm.s179172
Abstract: Abstract For the past several years, the implementation of pharmacogenetic (PGx) testing has become widespread in several centers and clinical practice settings. PGx testing may be ordered at the point-of-care when treatment is needed or… read more here.
Keywords: navigating ethical; ethical social; pgx testing; testing pediatrics ... See more keywords
Development and Implementation of In-House Pharmacogenomic Testing Program at a Major Academic Health System
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.712602
Abstract: Pharmacogenomics (PGx) studies how a person’s genes affect the response to medications and is quickly becoming a significant part of precision medicine. The clinical application of PGx principles has consistently been cited as a major… read more here.
Keywords: testing program; pgx; pharmacogenomic testing; implementation ... See more keywords
Clinical Value of Pharmacogenomic Testing in a Patient Receiving FOLFIRINOX for Pancreatic Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2018.01309
Abstract: Pharmacogenomic testing may have clinical value in the treatment of patients with gastrointestinal malignancies such as colorectal and pancreatic cancer. These types of cancer are often treated with combination chemotherapy regimens. These regimens can lead… read more here.
Keywords: value pharmacogenomic; pancreatic adenocarcinoma; clinical value; pharmacogenomic testing ... See more keywords
A Theory-Informed Systematic Review of Barriers and Enablers to Implementing Multi-Drug Pharmacogenomic Testing
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12111821
Abstract: PGx testing requires a complex set of activities undertaken by practitioners and patients, resulting in varying implementation success. This systematic review aimed (PROSPERO: CRD42019150940) to identify barriers and enablers to practitioners and patients implementing pharmacogenomic… read more here.
Keywords: pharmacogenomic testing; systematic review; informed systematic; barriers enablers ... See more keywords
Pharmacogenomics in Palliative Medicine
Sign Up to like & getrecommendations! Published in 2019 at "Indian Journal of Palliative Care"
DOI: 10.4103/ijpc.ijpc_46_19
Abstract: Pain relief is a basic human right.[1,2] Progress in the domain of pain management, particularly in that of cancer, is quite slow and remains as one of the feared aspects of the disease.[3] On an… read more here.
Keywords: care; medicine; pain; pain management ... See more keywords