Pharmacokinetic Evaluation of Two Nicotine Patches in Smokers
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.431
Abstract: Smoking continues to be a major preventable cause of early mortality worldwide, and nicotine replacement therapy has been demonstrated to increase rates of abstinence among smokers attempting to quit. Nicotine transdermal systems (also known as… read more here.
Keywords: replacement; evaluation two; pharmacokinetic evaluation; nicotine patches ... See more keywords
Synthesis, structural, cytotoxic and pharmacokinetic evaluation of some thiosemicarbazone derivatives.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.22512
Abstract: Iron(III) and nickel(II) complexes bearing a thiosemicarbazone framework were synthesized by a one-pot synthesis method. The structures were characterized by elemental analysis, IR, 1 H NMR, APCI Mass, conductivity, magnetic moment measurements. Molecular and crystal structures… read more here.
Keywords: pharmacokinetic evaluation; cytotoxic pharmacokinetic; synthesis structural; evaluation thiosemicarbazone ... See more keywords
Pharmacokinetic evaluation, molecular docking and in vitro biological evaluation of 1, 3, 4-oxadiazole derivatives as potent antioxidants and STAT3 inhibitors
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmaceutical Analysis"
DOI: 10.1016/j.jpha.2018.12.002
Abstract: 1, 3, 4-Oxadiazole derivatives (4a–5f) were previously synthesized to investigate their anticancer properties. However, studies relating to their antioxidant potential and signal transducer and activator of transcription (STAT) inhibition have not been performed. We investigated… read more here.
Keywords: pharmacokinetic evaluation; oxadiazole derivatives; evaluation molecular; evaluation ... See more keywords
Pharmacokinetic Evaluation of Empagliflozin in Healthy Egyptian Volunteers Using LC-MS/MS and Comparison with Other Ethnic Populations
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-02895-7
Abstract: The present study considered the pharmacokinetic evaluation of empagliflozin after administration to Egyptian volunteers, and the results were compared with other ethnic populations. The FDA recognizes that standard methods of defining racial subgroups are necessary… read more here.
Keywords: pharmacokinetic evaluation; ethnic populations; study; empagliflozin ... See more keywords
Pharmacokinetic evaluation of β-caryophyllene alcohol in rats and beagle dogs
Sign Up to like & getrecommendations! Published in 2018 at "Xenobiotica"
DOI: 10.1080/00498254.2017.1367441
Abstract: Abstract 1. β-caryophyllene alcohol (BCPA) has shown therapeutic promise in the treatment of asthma and inflammation with low toxicity. The aim of the current study was to report the pharmacokinetic profiles of BCPA in rats and… read more here.
Keywords: pharmacokinetic evaluation; bcpa; caryophyllene alcohol; evaluation caryophyllene ... See more keywords
Physicomechanical, stability, and pharmacokinetic evaluation of aceclofenac dimethyl urea cocrystals.
Sign Up to like & getrecommendations! Published in 2021 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-021-01938-7
Abstract: Poor physicomechanical properties and limited aqueous solubility restrict the bioavailability of aceclofenac when given orally. To improve its above properties, aceclofenac (ACE) was cocrystallized with dimethyl urea (DMU) in 1:2 molar ratio by dry and… read more here.
Keywords: pharmacokinetic evaluation; stability pharmacokinetic; dimethyl urea; aceclofenac ... See more keywords
Pharmacokinetic Evaluation of a Single Intramuscular High Dose versus an Oral Long-Term Supplementation of Cholecalciferol
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0169620
Abstract: Background and Objectives Vitamin D deficiency is frequent during the winter and occurs throughout the year in the elderly or patients suffering from autoimmune diseases. The objective of this study was to evaluate the pharmacokinetic… read more here.
Keywords: pharmacokinetic evaluation; supplementation; single intramuscular; evaluation single ... See more keywords
Pharmacokinetic Evaluation of Metabolic Drug Interactions between Repaglinide and Celecoxib by a Bioanalytical HPLC Method for Their Simultaneous Determination with Fluorescence Detection
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics11080382
Abstract: Since diabetes mellitus and osteoarthritis are highly prevalent diseases, combinations of antidiabetic agents like repaglinide (REP) and non-steroidal anti-inflammatory drugs (NSAID) like celecoxib (CEL) could be commonly used in clinical practice. In this study, a… read more here.
Keywords: pharmacokinetic evaluation; hplc; fluorescence; method ... See more keywords