Articles with "pharmacokinetic exposures" as a keyword



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Pharmacokinetic Exposures Associated With Oral Administration of Sorafenib in Dogs With Spontaneous Tumors

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Published in 2022 at "Frontiers in Veterinary Science"

DOI: 10.3389/fvets.2022.888483

Abstract: Sorafenib is a multi-kinase small molecule inhibitor that targets serine/threonine and tyrosine kinases including the RAF kinase family, VEGFR-2, and PDGFR. The aim of this study was to evaluate the systemic pharmacokinetics of a previously… read more here.

Keywords: administration; serum; pharmacokinetic exposures; sorafenib ... See more keywords