Pharmacokinetic, Safety, and Tolerability Evaluations of Gepotidacin (GSK2140944) in Healthy Japanese Participants
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DOI: 10.1002/cpdd.1192
Abstract: Gepotidacin is a novel, bactericidal, first‐in‐class triazaacenaphthylene antibiotic in late‐phase development for uncomplicated urinary tract infection and uncomplicated urogenital gonorrhea. Two clinical studies were conducted to assess the pharmacokinetics (PK) and interethnic comparisons of oral… read more here.
Keywords: healthy japanese; tolerability; pharmacokinetic safety; tolerability evaluations ... See more keywords
Phase 1 randomized pharmacokinetic and safety study of a 90‐day tenofovir vaginal ring in the United States
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the International AIDS Society"
DOI: 10.1002/jia2.26223
Abstract: Tenofovir‐based oral pre‐exposure prophylaxis is currently approved for HIV prevention; however, adherence in women has been low. A vaginal gel containing tenofovir (TFV) demonstrated partial protection to HIV but protection was not confirmed in additional… read more here.
Keywords: safety study; randomized pharmacokinetic; safety; phase randomized ... See more keywords