Articles with "pharmacokinetics bioequivalence" as a keyword



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Pharmacokinetics, Bioequivalence, and Safety of 2 Formulations of Hydroxychloroquine Tablets in Healthy Chinese Volunteers Under Fasting and Fed Conditions

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Published in 2022 at "Clinical Pharmacology in Drug Development"

DOI: 10.1002/cpdd.1166

Abstract: The purpose of this trial was to evaluate the pharmacokinetics (PK), bioequivalence (BE), and safety of 2 preparations of hydroxychloroquine (200‐mg tablet) under fasting and fed conditions. A total of 180 subjects (fasting condition: n… read more here.

Keywords: safety; fasting fed; pharmacokinetics bioequivalence; fed conditions ... See more keywords
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The Pharmacokinetics and Bioequivalence of Desvenlafaxine Succinate in Chinese Healthy Subjects Under Fasting and Fed States.

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Published in 2023 at "Clinical pharmacology in drug development"

DOI: 10.1002/cpdd.1272

Abstract: Desvenlafaxine succinate is a selective serotonin-norepinephrine reuptake inhibitor for the treatment of major depressive disorder. The pharmacokinetic profile of desvenlafaxine succinate at the clinically recommended dose of 50 mg in Chinese healthy subjects has been reported… read more here.

Keywords: fasting fed; desvenlafaxine succinate; pharmacokinetics bioequivalence; chinese healthy ... See more keywords