Articles with "pharmacokinetics dose" as a keyword



Population pharmacokinetics and dose-response relationship of levetiracetam in adult patients with epilepsy

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Published in 2017 at "Epilepsy Research"

DOI: 10.1016/j.eplepsyres.2017.02.011

Abstract: Levetiracetam (LEV) is commonly used as a mono- or adjunctive therapy for treating patients with partial and generalized epilepsy. This study aimed to develop a population pharmacokinetic (PK) model of LEV, based on sparse data,… read more here.

Keywords: dose response; pharmacokinetics dose; population pharmacokinetics; lev ... See more keywords

Pharmacokinetics and Dose Proportionality Study of a Novel Antiparkinsonian Agent, a 1H-1,2,4-Triazol-3-ylthio-conjugate of Prottremine

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Published in 2024 at "Molecules"

DOI: 10.3390/molecules29184498

Abstract: The novel antiparkinsonian agent PA-96 is the focus of our research. PA-96 supported the survival of cultured naïve dopamine neurons, alleviated motor deficits in MPTP and haloperidol-based mice models of Parkinson’s disease, and increased the… read more here.

Keywords: agent; dose proportionality; novel antiparkinsonian; antiparkinsonian agent ... See more keywords