Population pharmacokinetics and dosing optimization of olanzapine in Chinese paediatric patients: Based on the impact of sex and concomitant valproate on clearance
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DOI: 10.1111/jcpt.13770
Abstract: Olanzapine is an atypical antipsychotic drug used for mental disorders. There are limited studies providing sufficient pharmacokinetic data, thus the variability of concentrations of olanzapine used in Chinese paediatric patients aged 10 to 17 years remains… read more here.
Keywords: optimization olanzapine; paediatric patients; dosing optimization; chinese paediatric ... See more keywords
PP-50 Population pharmacokinetics and dosing optimisation of latamoxef in neonates
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DOI: 10.1136/archdischild-2017-esdppp.67
Abstract: Background Latamoxef, a new broad-spectrum oxac-ephem antibiotic, was used off-label in neonates. The present study aims to evaluate pharmacokinetics of latamoxef in neonates and establish appropriate dosing regimen. Methods Blood samples were collected from neonates… read more here.
Keywords: latamoxef neonates; optimisation latamoxef; population pharmacokinetics; pharmacokinetics dosing ... See more keywords
PP-49 Population pharmacokinetics and dosing optimisation of cefoperazone in children
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DOI: 10.1136/archdischild-2017-esdppp.94
Abstract: Background Cefoperazone is used in children with sus-pected or documented Gram-negative serious infections. Currently, its use is off-label partly because of lack of phar-macokinetic studies. Our aim was to evaluate the pop-ulation pharmacokinetics of Cefoperazone… read more here.
Keywords: cefoperazone; cefoperazone children; population pharmacokinetics; pharmacokinetics dosing ... See more keywords
P113 Population pharmacokinetics and dosing optimization of azlocillin in neonates
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DOI: 10.1136/archdischild-2019-esdppp.151
Abstract: Background Azlocillin is prescribed for the treatment of infections in neonatal clinical practice, however, the optimized dose is still questionable due to the lack of pharmacokinetic study Thus, we aim to evaluate the population pharmacokinetics… read more here.
Keywords: azlocillin; p113 population; population pharmacokinetics; pharmacokinetics dosing ... See more keywords