Population pharmacokinetics of intravenous and oral ciprofloxacin in children to optimize dosing regimens.
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DOI: 10.1007/s00228-021-03174-1
Abstract: PURPOSE This study aimed to characterize pharmacokinetics of intravenous and oral ciprofloxacin in children to optimize dosing scheme. METHODS Children treated with ciprofloxacin were included. Pharmacokinetics were described using non-linear mixed-effect modelling and validated with… read more here.
Keywords: intravenous oral; children optimize; pharmacokinetics intravenous; ciprofloxacin ... See more keywords
Population pharmacokinetics of intravenous fosfomycin: dose optimization for critically ill patients with and without kidney replacement therapy
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DOI: 10.1128/aac.01779-24
Abstract: ABSTRACT We investigated the pharmacokinetics (PK) of intravenous fosfomycin in critically ill patients undergoing different types of kidney replacement therapy (KRT) to identify optimized dosing regimens for patient care. Four prospective, observational studies contributed data… read more here.
Keywords: pharmacokinetics intravenous; ill patients; replacement therapy; kidney replacement ... See more keywords
Population Pharmacokinetics of Intravenous Acyclovir in Oncologic Pediatric Patients
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DOI: 10.3389/fphar.2022.865871
Abstract: Background: Acyclovir represents the first-line prophylaxis and therapy for herpes virus infections. However, its pharmacokinetics in children exposes them to the risk of ineffective or toxic concentrations. The study was aimed at investigating the population… read more here.
Keywords: oncologic pediatric; intravenous acyclovir; pharmacokinetics intravenous; population pharmacokinetics ... See more keywords