Population pharmacokinetics of intravenous and oral ciprofloxacin in children to optimize dosing regimens.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of clinical pharmacology"
DOI: 10.1007/s00228-021-03174-1
Abstract: PURPOSE This study aimed to characterize pharmacokinetics of intravenous and oral ciprofloxacin in children to optimize dosing scheme. METHODS Children treated with ciprofloxacin were included. Pharmacokinetics were described using non-linear mixed-effect modelling and validated with… read more here.
Keywords: intravenous oral; children optimize; pharmacokinetics intravenous; ciprofloxacin ... See more keywords
Population Pharmacokinetics of Intravenous Acyclovir in Oncologic Pediatric Patients
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.865871
Abstract: Background: Acyclovir represents the first-line prophylaxis and therapy for herpes virus infections. However, its pharmacokinetics in children exposes them to the risk of ineffective or toxic concentrations. The study was aimed at investigating the population… read more here.
Keywords: oncologic pediatric; intravenous acyclovir; pharmacokinetics intravenous; population pharmacokinetics ... See more keywords