Ocular Pharmacokinetics of Intravitreally Injected Protein Therapeutics: Comparison among Standard-of-Care Formats.
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DOI: 10.1021/acs.molpharmaceut.0c01218
Abstract: The current standard of care for antivascular endothelial growth factor (VEGF) treatment requires frequent intravitreal (IVT) injections of protein therapeutics, as a result of limited retention within the eye. A thorough understanding of the determinants… read more here.
Keywords: pharmacokinetics intravitreally; protein therapeutics; ocular pharmacokinetics; care ... See more keywords