Pharmacokinetics of isoniazid in children with tuberculosis—A comparative study at two doses
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DOI: 10.1002/ppul.24624
Abstract: To compare the pharmacokinetics of isoniazid (INH) at doses 5 and 10 mg/kg/day. read more here.
Keywords: comparative study; study two; children tuberculosis; isoniazid children ... See more keywords
Pharmacokinetics of isoniazid: The good, the bad, and the alternatives.
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DOI: 10.1016/j.tube.2019.04.012
Abstract: Although isoniazid (INH) has been successful in treating Tuberculosis (TB) since its introduction in 1952, there has been continual reports of drug-associated hepatotoxicity in TB patients. These toxic side effects may reveal more about the… read more here.
Keywords: isoniazid good; metabolism; good bad; drug ... See more keywords
Effect of efavirenz-based antiretroviral therapy and high-dose rifampicin on the pharmacokinetics of isoniazid and acetyl-isoniazid
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DOI: 10.1093/jac/dky378
Abstract: Objectives To describe the pharmacokinetics of isoniazid and acetyl-isoniazid in TB/HIV-coinfected patients, and assess the effects of efavirenz co-administration and a 50% increase in the dose of rifampicin on the pharmacokinetic parameters of isoniazid and… read more here.
Keywords: dose rifampicin; isoniazid; isoniazid acetyl; pharmacokinetics isoniazid ... See more keywords