Articles with "pharmacokinetics ivosidenib" as a keyword



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Effect of itraconazole, food, and ethnic origin on the pharmacokinetics of ivosidenib in healthy subjects

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Published in 2019 at "European Journal of Clinical Pharmacology"

DOI: 10.1007/s00228-019-02673-6

Abstract: PurposeTo assess the effect of ethnicity, food, and itraconazole (strong CYP3A4 inhibitor) on the pharmacokinetics of ivosidenib after single oral doses in healthy subjects.MethodsThree phase 1 open-label studies were performed. Study 1: Japanese and Caucasian… read more here.

Keywords: pharmacokinetics ivosidenib; effect; healthy subjects; subjects received ... See more keywords