Influence of CYP2D6*5 and *10 polymorphism on the pharmacokinetics of nebivolol in healthy Chinese subjects
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DOI: 10.1111/jcpt.13155
Abstract: Nebivolol, a selective β1 adrenoreceptor antagonist, is predominantly metabolized by cytochrome P450 (CYP)2D6 and shows a wide interindividual variability in pharmacokinetics. The present study was conducted to evaluate the effects of the major CYP2D6 polymorphisms… read more here.
Keywords: healthy chinese; cyp2d6 polymorphism; pharmacokinetics nebivolol; polymorphism pharmacokinetics ... See more keywords