Effect of Upadacitinib on the Pharmacokinetics of Rosuvastatin or Atorvastatin in Healthy Subjects.
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DOI: 10.1002/cpdd.957
Abstract: This phase 1, 2-part, 2-period, open-label, drug-drug interaction study evaluated the potential for pharmacokinetic interactions between upadacitinib and rosuvastatin, an organic anion transporting polypeptide (OATP) 1B1 and breast cancer resistance protein substrate, or atorvastatin, a… read more here.
Keywords: effect upadacitinib; part; pharmacokinetics rosuvastatin; effect ... See more keywords
Pharmacokinetics of Rosuvastatin: A Systematic Review of Randomised Controlled Trials in Healthy Adults
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DOI: 10.1007/s40262-020-00978-9
Abstract: Background Rosuvastatin is a lipid-lowering drug that works by inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme responsible for producing cholesterol in humans. The pharmacokinetic data of rosuvastatin are considerably variable across studies. Objective To… read more here.
Keywords: randomised controlled; healthy adults; pharmacokinetics rosuvastatin; rosuvastatin ... See more keywords
Effects of Ethanolic Extract of Schisandra sphenanthera on the Pharmacokinetics of Rosuvastatin in Rats
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DOI: 10.2147/dddt.s364234
Abstract: Purpose Wuzhi capsule (WZ) is a proprietary Chinese medicine prepared from the ethanolic extract of Schisandra sphenanthera that is commonly used to treat liver injury. Statins are widely used in patients with hyperlipidemia, coronary heart… read more here.
Keywords: ethanolic extract; group; schisandra sphenanthera; pharmacokinetics rosuvastatin ... See more keywords