Pharmacokinetics of TKM-130803 in Sierra Leonean patients with Ebola virus disease: plasma concentrations exceed target levels, with drug accumulation in the most severe patients
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DOI: 10.1016/j.ebiom.2019.102601
Abstract: Background TKM-130803 is a specific anti-EBOV therapeutic comprised of two small interfering RNAs (siRNA) siLpol-2 and siVP35-2. The pharmacokinetics (PK) of these siRNAs was defined in Ebola virus disease (EVD) patients, with reference to efficacy… read more here.
Keywords: pharmacokinetics tkm; tkm 130803; ebola virus; virus disease ... See more keywords