Influence of the skeletal muscle index on pharmacokinetics and toxicity of fluorouracil
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DOI: 10.1002/cam4.5118
Abstract: The body composition of patients has been associated with tolerability and effectiveness of anticancer therapy. This study aimed to assess the influence of the skeletal muscle index (SMI) on the pharmacokinetics and toxicity of fluorouracil. read more here.
Keywords: muscle index; pharmacokinetics toxicity; toxicity fluorouracil; influence skeletal ... See more keywords
Isobavachalcone: A comprehensive review of its plant sources, pharmacokinetics, toxicity, pharmacological activities and related molecular mechanisms
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DOI: 10.1002/ptr.7520
Abstract: Isobavachalcone (IBC), also known as isobapsoralcone, is a natural flavonoid widely derived from many medicinal plants, including Fabaceae, Moraceae, and so forth. IBC has been paid more and more attention by researchers in recent years… read more here.
Keywords: ibc; pharmacokinetics toxicity; plant sources; sources pharmacokinetics ... See more keywords
Pharmacokinetics and toxicity evaluation following oral exposure to bisphenol F.
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DOI: 10.1007/s00204-022-03246-w
Abstract: Bisphenol F is a substitute material for bisphenol A and is widely used in household products as a raw material for polycarbonate resin, epoxy resin, and plastic reinforcement. It is known to be mainly used… read more here.
Keywords: bisphenol; evaluation; pharmacokinetics toxicity; day ... See more keywords
Biodistribution, pharmacokinetics and toxicity evaluation of mannosylated gelatin nanoparticles of linezolid for anti-tubercular therapy
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DOI: 10.1080/10667857.2020.1816021
Abstract: The present study explores the therapeutic potential of gelatin nanoparticles as a carrier for the delivery of linezolid, a repurposed drug for the treatment of Mycobactrium tuberculosis. However, ... read more here.
Keywords: biodistribution pharmacokinetics; toxicity evaluation; mannosylated gelatin; pharmacokinetics toxicity ... See more keywords
Pharmacological Activity, Pharmacokinetics, and Toxicity of Timosaponin AIII, a Natural Product Isolated From Anemarrhena asphodeloides Bunge: A Review
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DOI: 10.3389/fphar.2020.00764
Abstract: Anemarrhena asphodeloides Bunge is a famous Chinese Materia Medica and has been used in traditional Chinese medicine for more than two thousand years. Steroidal saponins are important active components isolated from A. asphodeloides Bunge. Among… read more here.
Keywords: aiii; pharmacokinetics toxicity; asphodeloides bunge; timosaponin aiii ... See more keywords
Oridonin: A Review of Its Pharmacology, Pharmacokinetics and Toxicity
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DOI: 10.3389/fphar.2021.645824
Abstract: Oridonin, as a natural terpenoids found in traditional Chinese herbal medicine Isodon rubescens (Hemsl.) H.Hara, is widely present in numerous Chinese medicine preparations. The purpose of this review focuses on providing the latest and comprehensive… read more here.
Keywords: medicine; pharmacology pharmacokinetics; pharmacokinetics toxicity; pharmacology ... See more keywords
Jatrorrhizine: A Review of Sources, Pharmacology, Pharmacokinetics and Toxicity
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DOI: 10.3389/fphar.2021.783127
Abstract: Jatrorrhizine, an isoquinoline alkaloid, is a bioactive metabolite in common medicinal plants, such as Berberis vernae Schneid., Tinospora sagittata (Oliv.) Gagnep. and Coptis chinensis Franch. These plants have been used for centuries in traditional medicine… read more here.
Keywords: sources pharmacology; pharmacokinetics toxicity; pharmacology; jatrorrhizine ... See more keywords
Tubeimoside-1: A review of its antitumor effects, pharmacokinetics, toxicity, and targeting preparations
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.941270
Abstract: Tubeimoside-1 (TBMS-1), a natural triterpenoid saponin found in traditional Chinese herbal medicine Bolbostemmatis Rhizoma, is present in numerous Chinese medicine preparations. This review aims to comprehensively describe the pharmacology, pharmacokinetics, toxicity and targeting preparations of… read more here.
Keywords: pharmacokinetics toxicity; pharmacology; toxicity targeting; medicine ... See more keywords