Population pharmacokinetics of valproic acid in epileptic children: Effects of clinical and genetic factors
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2018.06.033
Abstract: &NA; Valproic acid (VPA) is a first‐line anti‐epileptic drug that is used in the treatment of generalized and partial seizures. Gene variants had been proved to influence the pharmacokinetics (PK) of VPA and contribute to… read more here.
Keywords: vpa; gene variants; pharmacokinetics valproic; valproic acid ... See more keywords
Comparative pharmacokinetics of valproic acid among Pakistani and South Korean patients: A population pharmacokinetic study
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0272622
Abstract: Purpose The pharmacokinetics of valproic acid have been evaluated in a variety of populations however, the comparison in two different populations was yet to be reported. This study is aimed to compare the pharmacokinetics of… read more here.
Keywords: pakistani south; south korean; valproic acid; pharmacokinetics valproic ... See more keywords